View abstract. Arch Dermatol.Res 2003;295(3):117-123. Irritation of the Skin 5. View abstract. View abstract. Brosche, T. and Platt, D. [Garlic as phytogenic antilipemic agent. 2008;138(6):996-1003. Garlic might also increase the risk of bleeding and cause allergic reactions in some people. The primary side effect of garlic consumption is its blood-thinning properties. Steinmetz et al., American Journal of Epidemiology: "Vegetables, fruit, and colon cancer in the Iowa Women's Health Study. Lipids Health Dis. Eating too much garlic may cause issues like bloating, gas, and heartburn. View abstract. Kim H, Keum N, Giovannucci EL, Fuchs CS, Bao Y. Garlic intake and gastric cancer risk: results from two large prospective US cohort studies. Toxicol.Appl.Pharmacol. Gardner CD, Lawson LD, Block E, et al. Lachter, J., Babich, J. P., Brookman, J. C., and Factor, A. Y. Garlic: a way out of work. Association and mechanism of garlic consumption with gastrointestinal cancer risk: A systematic review and meta-analysis. Arch Intern Med 1999;159:2484-5. Garlic as an antioxidant: the good, the bad and the ugly.Phytotherapy research : PTRvol. View abstract. The role of garlic in hepatopulmonary syndrome: a randomized controlled trial. Taking garlic along with medications that lower blood pressure might cause blood pressure to go too low. J Nutr.Biochem. 2012;50(11):778-786. 2003;55(2):199-202. View abstract. View abstract. Sensitivity to diallyl disulfide in a Spanish population. Effect of topical garlic on wound healing and scarring: A clinical trial. 2004;92(4):701-706. Dunstan, J. This might decrease how well atazanavir works. View abstract. Josling P. Preventing the common cold with a garlic supplement: a double-blind, placebo-controlled survey. Zhang, L., Gail, M. H., Wang, Y. Q., Brown, L. M., Pan, K. F., Ma, J. L., Amagase, H., You, W. C., and Moslehi, R. A randomized factorial study of the effects of long-term garlic and micronutrient supplementation and of 2-wk antibiotic treatment for Helicobacter pylori infection on serum cholesterol and lipoproteins. 2007;25(4):164-168. View abstract. Stevinson C, Pittler MH, Ernst E. Garlic for treating hypercholesterolemia: a meta-analysis of randomized clinical trials. Controlled double-blind study of subjects with reduced HDL2-cholesterol]. 2006;136(3 Suppl):816S-820S. What is the healthiest way to eat garlic? Fleischer S, Bayerl C, and Jung EG. Gardner CD, Chatterjee L, and Carlson J. Coughing up blood. Effect of dietary garlic (Allium Sativum) on the blood pressure in humans--a pilot study. Journal of Medical Council of Islamic Republic of Iran (J MED COUNC ISLAMIC REPUB IRAN) 2005;23(3):319. Challier, B., Perarnau, J. M., and Viel, J. F. Garlic, onion and cereal fibre as protective factors for breast cancer: a French case-control study. Dirsch, V. M., Gerbes, A. L., and Vollmar, A. M. Ajoene, a compound of garlic, induces apoptosis in human promyeloleukemic cells, accompanied by generation of reactive oxygen species and activation of nuclear factor kappaB. Pushing the Envelope of Nutrition Support: Complementary Therapies. View abstract. View abstract. In: Wagner H and Farnsworth NR. View abstract. Imai J, Ide N, Nagae S, et al. in an ovariectomized rat model of osteoporosis. Eight weeks of supplementation with a multi-ingredient weight loss product enhances body composition, reduces hip and waist girth, and increases energy levels in overweight men and women. Therefore, those who already have the problem of bad breath should not eat garlic too much. Dalmartello M, Turati F, Zhang ZF, et al. View abstract. Garcia-Anoveros, J. and Nagata, K. TRPA1. The effect of the aged garlic extract, 'Kyolic', on the development of experimental atherosclerosis. Papageorgiou, C., Corbet, J. P., Menezes-Brandao, F., Pecegueiro, M., and Benezra, C. Allergic contact dermatitis to garlic (Allium sativum L.). Arztliche Forschung 1988;3:3-8. Garlic is more toxic than onions with raw garlic, toxic ingestion is around 1 gram per 5 pounds, and with onions it is 1 gram per pound. View abstract. View abstract. View abstract. It also found that allicin had antifungal properties, including against Candida albicans, which causes yeast infections. Ashraf, R., Aamir, K., Shaikh, A. R., and Ahmed, T. Effects of garlic on dyslipidemia in patients with type 2 diabetes mellitus. Arzliche Forschung 1988;3:1-8. Inhibition of cholesterol and fatty acid biosynthesis in liver enzymes and chicken hepatocytes by polar fractions of garlic. Nutr Rev 2013;71:282-99. Effect of garlic (Allium sativum) on lipid peroxidation in experimental myocardial infarction in rats. As per some studies, garlic may also cause profuse sweating in certain individuals (15). Hussain, S. P., Jannu, L. N., and Rao, A. R. Chemopreventive action of garlic on methylcholanthrene-induced carcinogenesis in the uterine cervix of mice. 2012;92:1892-1902. Ackermann RT, Mulrow CD, Ramirez G, et al. It can also cause heartburn, upset stomach, and diarrhea. View abstract. Zini A, Mann J, Mazor S, Vered Y. Lipids 1996;31:1269-76. Groppo, F. C., Ramacciato, J. C., Simoes, R. P., Florio, F. M., and Sartoratto, A. Antimicrobial activity of garlic, tea tree oil, and chlorhexidine against oral microorganisms. J.Burn Care Res. 2006;20(1):21-27. Circulation 1999;99(8):1123. View abstract. View abstract. Free Radic.Res. Garlic might reduce how much isoniazid the body absorbs. Rahmani M, Tabari AK, Niaki MRK, and et al. View abstract. BMJ 2019;366:l5016. 3-21-1990;82(6):478-485. Yuncu, M., Eralp, A., and Celik, A. Khoo YS, Aziz Z. Garlic supplementation and serum cholesterol: a meta-analysis. The NCCIH suggests avoiding garlic supplements prior to surgery as well and points out that garlic supplements may interfere with the effectiveness of certain medications, such as saquinavir, a drug used to treat HIV. View abstract. Arzneimittelforschung 1992;42:1223-7. Breast Cancer Res Treat 1995;33:163-70. Nutr Res 2000;20:575-84. Arch Intern Med 2007;167:346-53. View abstract. Free Radic.Biol Med 10-1-2000;29(7):602-611. Atherosclerosis 1997;132:37-42. Mader FH. 2020:postgradmedj-2019-137267. View abstract. Borrelli F, Capasso R, Izzo AA. McCrindle BW, Helden E, Conner WT. View abstract. Onion and garlic intake and breast cancer, a case-control study in Puerto Rico. Talk to your doctor or surgeon prior to taking garlic supplements. J Hypertens 1994;12:463-8. View abstract. View abstract. 2011;28(3):589-598. 2004;50(4):467-472. Appl Environ.Microbiol 1996;62(11):4238-4242. Fleischauer AT, Poole C, Arab L. Garlic consumption and cancer prevention: meta-analyses of colorectal and stomach cancers. Int J STD AIDS. To combat this, you could reduce the amount of garlic you eat, use probiotics for optimal gut health or try adding good smelling herbs to your diet. Arzneimittelforschung 1986;36:766-8. Life Sci. Get emergency medical help if you have any of these signs of an allergic reaction while taking garlic: hives; difficult breathing; swelling of your face, lips, tongue, or throat. J Nutr 1983;113:1746-55. View abstract. Taking garlic may stimulate this nerve to release neuronal signaling molecules called neuropeptides that rush to the membrane covering your brain and cause headaches. Liu, L. and Yeh, Y. Y. Inhibition of cholesterol biosynthesis by organosulfur compounds derived from garlic. Vaginal yeast infections (thrush): What helps? Int J Cancer 4-1-1994;57(1):38-46. Bimmermann A, Weingart K, and Schwartzkopff W. Allium sativum: Studie zur Wirksamkeit bei Hyperlipoproteinamie. View abstract. Afarid M, Sadeghi E, Johari M, Namvar E, Sanie-Jahromi F. Evaluation of the effect of garlic tablet as a complementary treatment for patients with diabetic retinopathy. View abstract. Effect of samgyetang feeding on plasma lipids, glucose, glycosylated hemoglobin, and stress-induced gastric ulcers in mice. A skin condition most commonly diagnosed in young children that causes redness, dryness, itchiness, and inflammation. Does garlic elevate blood pressure levels? Takeuchi, S., Matsuzaki, Y., Ikenaga, S., Nishikawa, Y., Kimura, K., Nakano, H., and Sawamura, D. Garlic-induced irritant contact dermatitis mimicking nail psoriasis. Heart Related Side Effects 3. View abstract. View abstract. J Nutr. View abstract. Ashraf, M. Z., Hussain, M. E., and Fahim, M. Endothelium mediated vasorelaxant response of garlic in isolated rat aorta: role of nitric oxide. Fernandez-Vozmediano JM, Armario-Hita JC, Manrique-Plaza A. Allergic contact dermatitis from diallyl disulfide. Clinical assessment of potential cytochrome P450-mediated herb-drug interactions. Qureshi AA, Crenshaw TD, and Abuirmeileh N. Influence of minor plant constituents on porcine hepatic lipid metabolism. View abstract. De Santos O and Grunwald J. Knowles, L. M. and Milner, J. 2016;25(4):624-33. Ide N, Lau BH. J Nutr 2001;131:985S-8S. View abstract. Siegers CP, Steffen B, Robke A, and et al. B., and Eling, T. E. Diallyl disulfide (DADS) induces the antitumorigenic NSAID-activated gene (NAG-1) by a p53-dependent mechanism in human colorectal HCT 116 cells. 192,4 (1996): 373-4. Clin.Nutr. Lopez, H. L., Ziegenfuss, T. N., Hofheins, J. E., Habowski, S. M., Arent, S. M., Weir, J. P., and Ferrando, A. Raw garlic consumption and lung cancer in a Chinese population. View abstract. View abstract. View abstract. Int J Cancer 4-1-1992;50(6):876-880. Eur.J Obstet.Gynecol.Reprod.Biol. Information from this source is evidence-based and objective, and without commercial influence. Kaplan, B., Schewach-Millet, M., and Yorav, S. Factitial dermatitis induced by application of garlic. Fani, M. M., Kohanteb, J., and Dayaghi, M. Inhibitory activity of garlic (Allium sativum) extract on multidrug-resistant Streptococcus mutans. View abstract. Vegetables, fruit, and colon cancer in the Iowa Women's Health Study. Common side effects (especially when eating raw garlic) may include: heartburn, burning in your mouth or throat; This is not a complete list of side effects and others may occur. 1998;30(1):189-191. The effect of garlic (Allium sativum) supplementation on the lipid parameters and blood pressure levels in women with polycystic ovary syndrome: A randomized controlled trial. Effect of garlic on blood pressure: A systematic review and meta-analysis. View abstract. Hjorth, N. and Roed-Petersen, J. Evidence Report/Technology Assessment No. Preecampisia [sic] is an important complication of pregnancy which can result in morbidity and mortality in mother, fetus and the neonate. View abstract. 2006;20(6):504-510. Delaney, T. A. and Donnelly, A. M. Garlic dermatitis. Mennella JA, Beauchamp GK. Dillon, S. A., Lowe, G. M., Billington, D., and Rahman, K. Dietary supplementation with aged garlic extract reduces plasma and urine concentrations of 8-iso-prostaglandin F(2 alpha) in smoking and nonsmoking men and women. Garlic shows promise for improving some cardiovascular risk factors. Sarrell, E. M., Cohen, H. A., and Kahan, E. Naturopathic treatment for ear pain in children. Jpn.J Cancer Res 1999;90(6):614-621. Aydin A, Ersoz G, Tekesin O, et al. 2011;24(4):565-570. Int J Clin Pract 2021;75(12):e14974. Anthony, J. P., Fyfe, L., and Smith, H. Plant active components - a resource for antiparasitic agents? Zeybek, A., Cikler, E., Saglam, B., Ercan, F., Cetinel, S., and Sener, G. Aqueous garlic extract inhibits protamine sulfate-induced bladder damage. J Altern.Complement Med 2007;13(1):83-95. View abstract. Bordia, A., Verma, S. K., and Srivastava, K. C. Effect of garlic on platelet aggregation in humans: a study in healthy subjects and patients with coronary artery disease. Dhamija P, Malhotra S, Pandhi P. Effect of oral administration of crude aqueous extract of garlic on pharmacokinetic parameters of isoniazid and rifampicin in rabbits. Int J Dermatol 2005;44:612-5. She has 6 years of experience and works with clients around the world to help them reach their health and fitness goals. View abstract. J Orthomolec Med 1987;2(1):15-21. Prostaglandins Leukot Essent Fatty Acids 1996;55(3):201-205. View abstract. 1990;49(2):175-180. Prostaglandins Leukot.Essent.Fatty Acids 1995;53(6):397-400. 2020;19(2):1468-1471. Knox, J. and Gaster, B. Dietary supplements for the prevention and treatment of coronary artery disease. But if you are already on medications for high blood pressure, it may lead to hypotension (low blood pressure). View abstract. Delaha, E. C. and Garagusi, V. F. Inhibition of mycobacteria by garlic extract (Allium sativum). Lachmann, G., Lorenz, D., Radeck, W., and Steiper, M. [The pharmacokinetics of the S35 labeled labeled garlic constituents alliin, allicin and vinyldithiine]. View abstract. Contact allergy to garlic used for wound healing. View abstract. View abstract. Trop.Doct. A case of anaphylaxis after garlic ingestion: Is alliinase the only culprit allergen? Dizziness or weakness. Effect of purified allicin, the major ingredient of freshly crushed garlic, on cancer cell proliferation. View abstract. 2015;42(10):1026-7. Sangouni AA, Mohammad Hosseini Azar MR, Alizadeh M. Effect of garlic powder supplementation on hepatic steatosis, liver enzymes and lipid profile in patients with non-alcoholic fatty liver disease: a double-blind randomised controlled clinical trial. Overdoing it may result in stomach distress, bloating, diarrhea, poor breath, and unpleasant body odor. Gebhardt R, Beck H, and Wagner K. Inhibition of cholesterol biosynthesis by allicin and ajoene in rat hepatocytes and HepG2 cells. Risk factors for oesophageal cancer in northeast China. Many studies have found that garlic can reduce the chances that blood clots will form. Egen-Schwind C, Eckard R, Jekat FW, and et al. Phytother.Res 2000;14:200-2. View abstract. Mechanism of antioxidation, inhibiting carcinogenesis and modification of LDL of aged garlic extract. You WC, Blot WJ, Chang YS, et al. Allium vegetable consumption, garlic supplement intake, and female breast carcinoma incidence. Dent Traumatol 2022. Hum.Exp.Toxicol. Read more: Which Is Healthier, Raw or Cooked Garlic? Modulation of lipid profile by fish oil and garlic combination. Rahman K, Billington D. Dietary supplementation with aged garlic extract inhibits ADP-induced platelet aggregation in humans. View abstract. Su, Q. S., Tian, Y., Zhang, J. G., and Zhang, H. Effects of allicin supplementation on plasma markers of exercise-induced muscle damage, IL-6 and antioxidant capacity. WebThe primary side effect of garlic consumption is its blood-thinning properties. View abstract. Garlic is widely used in culinary delights and traditional home remedies. Randomized double-blind factorial trial of three treatments to reduce the prevalence of precancerous gastric lesions. 2009;23(4):513-518. Eur J Pharmacol 2001;433:177-85.. View abstract. A., Connock, M. J., and Maslin, D. J. Phytomedicine. Lembo, G., Balato, N., Patruno, C., Auricchio, L., and Ayala, F. Allergic contact dermatitis due to garlic (Allium sativum). View abstract. ", K. Reid, Experimental and Therapeutic Medicine: "Garlic lowers blood pressure in hypertensive subjects, improves arterial stiffness and gut microbiota: A review and meta-analysis. Does garlic induce labor in pregnant women? Ekeowa-Anderson, A. L., Shergill, B., and Goldsmith, P. Allergic contact cheilitis to garlic. Study on extending of the activity spectrum of a garlic preparation against candidiasis. Moriguchi T, Saito H, Nishiyama N. Aged garlic extract prolongs longevity and improves spatial memory deficit in senescence-accelerated mouse. Suzuki Y, Saito J, Misa K, Fukuhara N, Fukuhara A, Munakata M. A case of black garlic-induced pneumonia as an adverse reaction. View abstract. Davis, S. R., Perrie, R., and Apitz-Castro, R. The in vitro susceptibility of Scedosporium prolificans to ajoene, allitridium and a raw extract of garlic (Allium sativum). Rivlin, R. S. Historical perspective on the use of garlic. View abstract. Consumption of aqueous garlic extract leads to significant improvement in patients with benign prostate hyperplasia and prostate cancer. View abstract. Planta Med 1994;60:546-549. This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version.
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