permission provided that the original article is clearly cited. We conclude that there should be low threshold to recommend ophthalmic examination to patients with Cushings syndrome, and that a macular OCT is recommended during this examination. The transfusion rate was 50.0% (586/1173 patients). Prediction of blood transfusion after adult spinal deformity (ASD) surgery can identify at-risk patients and potentially reduce its utilization and the complications associated with it. This journal offers authors two options (Open Access or subscription) to publish their research. In conclusion, the paracrine release of IGF-1 from mesenchymal stem cells increases the expression of antioxidant marker SOD2, and the expression of SOD2 reduces oxidative stress as well as suppresses p53, leading to a reduction in cardiac senescence in D-galactose-stressed rats. European Journal of Internal Medicine is the official journal of the European Federation of Internal Medicine and is the reference scientific journal for the European academic and non-academic internists.The journal is devoted to promoting science and practice in internal medicine in Europe.
Purpose: To investigate the relationship between two distinct layers of macular vessel density (superficial vascular plexus (SVP) and deep vascular plexus (DVP)) and central visual field sensitivity (cVFS) in open-angle glaucoma (OAG) eyes with high myopia. 
The most recent (2021) Impact Factor forAnnals of Internal Medicineis 51.598 (Clarivate Analytics). We performed a systematic literature search in 11 databases on 21 May 2022. The most common presenting symptom was gastrointestinal bleeding (, Exosomal miRNAs have been studied in various cancers as minimally invasive biomarkers. Methods and Materials: A retrospective data analysis of patients treated for secondary aortoenteric fistulas in a single vascular institution between January 2005 and December 2018 was performed. Feature Papers represent the most advanced research with significant potential for high impact in the field. Results: Twenty-three patients with aortoenteric fistulas were treated in the target period. Published weekly online + 12 print issues per year, Physician Well-being & Professional Fulfillment, Racial Health Disparities, Prejudice and Violence, ACP's Vision for the U.S. Health Care System, Physician Well-being and Professional Fulfillment, Institutional customers have the option to, Contact ACP Member and Product Support at 800-523-1546, extension 2600 or 215-351-2600 (M - F, 9 a.m.- 5 p.m. On the testing data, the sensitivity was 80%, the positive predictive value 76%, and the F1-score was 78%. Researching a topic? In this systematic review and meta-analysis, we summarize available evidence on pachychoroid spectrum diseases in patients with Cushings. (2) Methods: This retrospective single-center study included 214 patients who underwent primary resection of PDAC from January 2000 to December 2018 at University Hospital Erlangen. Purpose: The effect of sarcopenia on the survival of patients with type 2 diabetes remains unclear.
Medical consultation talk show featuring Drs. Parasomnias are sleep disorders that involve abnormal behaviors, emotional experiences, perceptions, and dream activity, occurring during specific sleep stages or sleepwake transitions. MDPI stays neutral with regard to jurisdictional claims in published maps and institutional affiliations. All Rights Reserved. Pachychoroid spectrum diseases were relatively common in these patients: PPE in 20.8%, CSC in 7.7%, and PCV in 2.8%. Of note, most of the aforementioned inflammatory cytokines utilize the JAK/STAT pathway for downstream signal transduction, explaining the emerging role of JAK inhibitors in the therapeutic armamentarium of AD. ET) or. Beyond the Guidelines is a multimedia feature based on selected clinical conferences at Beth Israel Deaconess Medical Center (BIDMC). This Annals' "On Being a Doctor" Story Slam was made possible with generous support from the Josiah Macy Jr. Foundation. Annals Graphic Medicine brings together original graphic narratives, comics, animation/feature, and other creative forms by those who provide or receive health care. Annals of Internal Medicine is also available as a benefit of ACP membership. Please upgrade your browser to allow continued use of ACP websites. 
800-ACP-1915 (800-227-1915) or 215-351-2600. Geno Merli and Howard Weitz. This type of In order to be human-readable, please install an RSS reader. 
prior to publication. The model was assessed by its sensitivity, positive predictive value, F1-score, accuracy (ACC), and area under the curve (AUROC). (1) Background: Delay in therapy for pancreatic ductal adenocarcinoma (PDAC) may contribute to a worse outcome. Daniel Emil Tadeusz Raaschou-Pedersen, BSc, Print ISSN: 0003-4819 | Online ISSN: 1539-3704, Annals of Internal Medicine: Clinical Cases, Telehealth Strategies for Delivering Maternal Health Care, Outcomes in Patients With Atrial Fibrillation After Noncardiac Surgery. Of the differentially expressed 14 miRNAs, the top 2 up-regulated miRNAs (miR-205-5p and miR-429) and top 2 down-regulated miRNAs (miR-375-3p and miR-483-3p) were selected as ESCC target miRNAs. Exosomal miRNAs have been studied in various cancers as minimally invasive biomarkers. Individual and institutional subscriptions available. Offering guidance on clinical use cases, technology, regulations and waivers, and billing and coding. Building on the popular Annals' feature "On Being a Doctor," Annals hosted an "On Being a Doctor" Story Slam on November 18, 2015. On average, patients with Cushings syndrome have 49.5 m thicker subfoveal choroidal thickness compared to matched healthy individuals. Significant increases in cell viability and the expression of SOD2, as well as a reduction in oxidative stress and the suppression of p53, were found in D-galactose-stressed H9c2 cells cultured with a stem-cell-conditioned medium, whereas the depletion of IGF-1 in stem-cell-conditioned medium diminished the antiaging effect on H9c2 cells. Electronic delivery of journal content, exactly how you want it. After the rats had received mesenchymal stem cells, all the pathological conditions were significantly improved in D-galactose-stressed hearts. This study aimed to investigate in detail the mechanism. The aim of this study was to investigate the prognostic value of time from diagnosis to surgery in patients undergoing upfront surgery for primarily resectable pancreatic carcinoma. Interested in Becoming a Fellow? The AUROC was 0.84. There was also an association between mild COVID-19 symptoms with prior tuberculosis vaccination among cancer patients. JournalFinder uses smart search technology and field-of-research specific vocabularies to match your manuscript to Elsevier journals. quality clinical studies related to internal medicine; papers defining the unmet clinical needs in several areas of internal medicine; methodology of clinical research and critical reading of clinical studies; high-level subgroup or secondary analyses of the major clinical trials; experimental design of planned or ongoing large clinical trials. Conclusion: Cancer patients in SSA tend to have a relatively lower SARS-CoV-2 seroprevalence compared to potential blood donors recruited from the same geographic locations during the COVID-19 pandemic. Analyzed parameters included patients demographics, clinical presentation, diagnostic work-up, perioperative data and repair durability during follow-up.
Results: We recruited 28 unvaccinated and 22 vaccinated patients. Pelvic fixation was performed in 21.3% of patients and three-column osteotomies in 19.5% of cases. The most reported symptoms are fatigue, headache and attention/concentration issues, dyspnea and myalgia. This study aims to better understand the potential. You are using an outdated browser. Papers are submitted upon individual invitation or recommendation by the scientific editors and undergo peer review More evidence substantially links cortisol levels to the pachychoroid spectrum diseases. Cookie Settings, Terms and ConditionsPrivacy PolicyCookie NoticeSitemap, The Impact Factor of this journal is 7.749, ranking it 26 out of 171 in, With this journal indexed in 9 international databases, your published article can be read and cited by researchers worldwide, Pasquale Perrone-Filardi, Stefania Paolillo and 18 more, Discover options for sharing your research data, Publish your research output in a Research Elements journal, European Federation of Internal Medicine (EFIM). Cases showed higher level of anxiety and job demand compared to controls. Cardiovascular Disease in 2021 and beyondWhat Have We Learned and How Do We Move On? Hence, the scope of the present multicenter study was to compare the IOL power calculation accuracy in post-SMILE eyes between ray tracing and a range of empirically optimized formulae available in the ASCRS post-keratorefractive surgery IOL power online calculator. The Feature Paper can be either an original research article, a substantial novel research study that often involves Make your research data available, accessible, discoverable, and usable. Its content not only advances the science of medicine, but educates and entertains readers through a variety of features, such as: Read the journal in print or on any device. Surgery for Aortic Prosthetic Valve Endocarditis in the Transcatheter Era, White Matter Correlates of Early-Onset Bipolar Illness and Predictors of One-Year Recurrence of Depression in Adults with Bipolar Disorder, Cushings syndrome is a rare disease with an endogenous cause of excess cortisol secretion. Open AccessPasquale Perrone-Filardi, Stefania Paolillo and 18 more, Cristina Morelli, Gessica Ingrasciotta and 3 more, Maxime Samson, Barbara Nicolas and 15 more, 61 editors and editorial board members in 15 countries/regions, Gender Diversity Distribution of the Editors, Benchmark Gender Diversity distribution across Respiratory Medicine portfolio Editors. Exosomes were isolated from cultures of esophageal epithelial cell and ESCC cell. Experimental results from the in vitro model indicated that the elevation of oxidative stress, the expression of aging marker p53, and the suppression of antioxidant marker SOD2 could be found in D-galactose-stressed H9c2 cardiomyoblasts. The Consult Guys bring a new perspective to the art and science of medicine with lively discussion and analysis of real world cases and situations. In linear regression analysis, both SVP and DVP were significantly associated with cVFS in HMG eyes, but only SVP showed a significant correlation with cVFS in NMG eyes. After more than one decade since the introduction of SMILE, only one case report of cataract surgery with IOL implantation after SMILE is present in the peer-reviewed literature. Cell-based therapies show potential in the treatment of cardiac aging due to the characteristics of stem cells, including differentiation and the paracrine effect. Average patient age was 56 years and 63% were female. The aim of this study was to investigate the prognostic value of time from diagnosis to surgery in patients undergoing upfront surgery for primarily resectable pancreatic carcinoma. There were no differences in baseline demographic and pulmonary function testing (PFT) parameters. Paracrine IGF-1 Activates SOD2 Expression and Regulates ROS/p53 Axis in the Treatment of Cardiac Damage in D-Galactose-Induced Aging Rats after Receiving Mesenchymal Stem Cells, Cellular Senescence in Cardiovascular and Metabolic Diseases, IOL Power Calculations and Cataract Surgery in Eyes with Previous Small Incision Lenticule Extraction, Current Challenges and Advances in Cataract Surgery, MDPIs 2021 Young Investigator Awards in Medicine & PharmacologyWinners Announced, MDPIs 2021 Travel Awards in Medicine & PharmacologyWinners Announced, MRI and PET/MRI in Hematology and Oncology, Sterile Inflammation in Solid Organ Transplantation, Applied System on Biomedical Engineering, Healthcare and Sustainability, The 3rd International Electronic Conference on Brain Sciences (IECBS2022), ORLIAC 2022: XI International Academic Conference in Otorhinolaryngology, The 2nd Annual Rare and Genetic Kidney Disease Drug Development Summit, Management of Pituitary Tumors: Current and Future Treatment Options, Clinical Management of Major Bleeding and Coagulopathy Following Trauma, Clinical Research and Advances in Hemodialysis, Advances in Understanding the Pathogenesis and Pathophysiology of Orthopaedic-Related Infections, The Role of the Microenvironment in Multiple Myeloma: From Biology to Clinical Practice, Clinical Diagnosis and Management of Pregnancy Complications. A total of 180 articles were published in 2021. The use of artificial neural networks (ANNs) offers the potential for high predictive capability. Original graphic narratives on medically relevant topics. It is unknown whether COVID-19 vaccination mitigates against reduced aerobic capacity. The fistulous connection was located in 21 cases (91.3%) in the duodenum and in two cases (8.7%) in the small intestine. Such situations include those in which a guideline finds evidence insufficient to make a recommendation, a patient does not fit criteria mapped out in recommendations, or different organizations provide conflicting recommendations. Therefore, we designed a propensity score-matched population-based cohort study to compare the patients with diabetes with or without sarcopenia. Treating a patient? Cardiac computed tomography (CT) has evolved over the past 20 years from an alternative, promising noninvasive imaging modality to a Class I indication for the non-invasive evaluation of patients with low-to-intermediate, pre-test probability of coronary artery disease (CAD), as per the European Society, Cardiac computed tomography (CT) has evolved over the past 20 years from an alternative, promising noninvasive imaging modality to a Class I indication for the non-invasive evaluation of patients with low-to-intermediate, pre-test probability of coronary artery disease (CAD), as per the European Society of Cardiology (ESC) guidelines published in 2019 [], Background: Despite the high COVID-19 morbidity and mortality rates across the world, the reported rates in sub-Saharan Africa (SSA), which has a higher burden of other infectious diseases and overwhelmed healthcare systems, remain relatively low. Access Elseviers most recent Global Gender Report. For Eighteen patient and operative variables were used. Clinical experts provide opinions and comment on how they would approach the patient's care. In addition, the journal publishes personal narratives that convey the feeling and the art of medicine. Four selected exosomal miRNAs were validated in the plasma of 20 healthy controls (HCs) and 40 ESCC patients via quantitative reverse transcription-polymerase chain reaction. Continue the tradition of Fellowship by sharing your own experience and offering to support other members' candidacies. Patients and Methods: We included patients with type 2 diabetes and categorized them into two groups according to whether they had sarcopenia and compared their survival; patients in the groups were matched at a ratio of 1:2. Method: This retrospective cross-sectional study included 148 OAG eyes (64 highly myopic (HMG) and 84 non-highly myopic glaucomas (NMG)) as well as 54 healthy eyes. Compared with unvaccinated individuals, those vaccinated had higher VO, Aging is one of the causative agents associated with heart failure. A total of 1173. The expression of plasma exosomal miR-205-5p and miR-429 significantly increased, while that of plasma exosomal miR-375-3p was significantly reduced in ESCC patients compared to that in HCs. Studies were considered eligible if they performed retinal examination of a consecutive group of patients with Cushings syndrome using optical coherence tomography (OCT) scans. In addition, reduced aerobic capacity has been demonstrated in both, Patients previously infected with acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may experience post-acute adverse health outcomes, known as long COVID. articles published under an open access Creative Common CC BY license, any part of the article may be reused without To this end, the journal publishes original articles, editorials, reviews, internal medicine flashcards, and other information relevant to internal medicine and related fields. After more than one decade since the introduction of SMILE, only one case report. High myopia was defined as a spherical equivalent of less than 6.0 diopters or an axial length of 26.0 mm. The results are indicating the need for workplace health promotion activities based on stress and burnout management and prevention. Copyright 2022 Elsevier, except certain content provided by third parties, Cookies are used by this site. Methods: Individuals aged 18 to 65 years with laboratory-confirmed mild to moderate COVID-19 disease were invited to Ziv Medical Centre, Israel, three months after SARS-CoV-2 infection. A total of 1173 patients who underwent surgery for ASD were identified in the 20172019 NSQIP databases. progress in the field that systematically reviews the most exciting advances in scientific literature. Annals publishes clinically-relevant articles that promote excellence in medicine and influence patient care. Subscribe to receive issue release notifications and newsletters from MDPI journals, You can make submissions to other journals. This publication may be associated with a critical assessment by methodology experts commenting the methodology of the paper, strengths and potential limitations; acute and critical care medicine as well as emergency medicine to contribute to develop the new professional figure of the internist in the European hospitals.
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